C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synth
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000021443 Mthfd1-201 ENSMUSG00000021048 10090 + 12:76255232-76319820 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000021443
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000021443 11.179±3.37 7.826±1.53 13.604±0.69 12.864±3.76 6.575±0.75 10.057±0.77 6.728±0.46 61.052±2.12 51.998±13.35 18.082±2.48 9.788±0.57 14.890±5.53 19.588±9.38 1.885±0.20

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000105 IEA histidine biosynthetic process
GO:0004329 IBA formate-tetrahydrofolate ligase activity
GO:0004477 IBA methenyltetrahydrofolate cyclohydrolase activity
GO:0004488 IBA methylenetetrahydrofolate dehydrogenase (NADP+) activity
GO:0005524 IEA ATP binding
GO:0005739 IDA mitochondrion
GO:0005829 IBA cytosol
GO:0006164 IEA purine nucleotide biosynthetic process
GO:0006730 IBA one-carbon metabolic process
GO:0009086 IEA methionine biosynthetic process
GO:0009396 IEA folic acid-containing compound biosynthetic process
GO:0016020 IEA membrane
GO:0035999 IEA tetrahydrofolate interconversion
GO:0055114 IEA oxidation-reduction process
GO:0070062 IEA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000216605 MTHFD1-019 protein_coding Homo_sapiens 0 3336
ENST00000413059 MTHFD1P1-001 processed_pseudogene Homo_sapiens 0 2579
ENST00000545908 MTHFD1-002 protein_coding Homo_sapiens 0 3160
ENST00000553405 MTHFD1-008 retained_intron Homo_sapiens 0 800
ENST00000554353 MTHFD1-013 retained_intron Homo_sapiens 0 207
ENST00000554677 MTHFD1-009 retained_intron Homo_sapiens 0 514
ENST00000554739 MTHFD1-015 protein_coding Homo_sapiens 0 252
ENST00000554768 MTHFD1-005 protein_coding Homo_sapiens 0 263
ENST00000555252 MTHFD1-003 retained_intron Homo_sapiens 0 1873
ENST00000555709 MTHFD1-001 protein_coding Homo_sapiens 0 713
ENST00000556284 MTHFD1-012 processed_transcript Homo_sapiens 0 593
ENST00000556771 MTHFD1-018 retained_intron Homo_sapiens 0 453
ENST00000557539 MTHFD1-006 protein_coding Homo_sapiens 0 399

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