Warning (512): _cake_core_ cache was unable to write 'cake_dev_eng' to File cache [CORE/Cake/Cache/Cache.php, line 323]
Warning (512): _cake_model_ cache was unable to write 'default_citloci_list' to File cache [CORE/Cake/Cache/Cache.php, line 323]
Warning (512): _cake_model_ cache was unable to write 'default_citloci_list' to File cache [CORE/Cake/Cache/Cache.php, line 323]
Warning (512): _cake_model_ cache was unable to write 'default_citloci_transcripts' to File cache [CORE/Cake/Cache/Cache.php, line 323]
Warning (512): _cake_model_ cache was unable to write 'default_citloci_transcripts' to File cache [CORE/Cake/Cache/Cache.php, line 323]
Institute of Cardiovascular Regeneration Webtool Repository

C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info

Description: methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate syn
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000555709 MTHFD1-001 ENSG00000100714 9606 + 14:64388240-64418024 protein_coding

Expression Patterns

No expression data.

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000105 IEA histidine biosynthetic process
GO:0003824 IEA catalytic activity
GO:0004329 IBA formate-tetrahydrofolate ligase activity
GO:0004477 IBA methenyltetrahydrofolate cyclohydrolase activity
GO:0004486 TAS methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity
GO:0004488 IEA:IBA methylenetetrahydrofolate dehydrogenase (NADP+) activity
GO:0005524 IEA ATP binding
GO:0005829 IBA cytosol
GO:0006164 IEA purine nucleotide biosynthetic process
GO:0006730 IBA one-carbon metabolic process
GO:0006766 TAS vitamin metabolic process
GO:0006767 TAS water-soluble vitamin metabolic process
GO:0009086 IEA methionine biosynthetic process
GO:0009396 IEA folic acid-containing compound biosynthetic process
GO:0016020 IDA membrane
GO:0035999 IEA tetrahydrofolate interconversion
GO:0044281 TAS small molecule metabolic process
GO:0046655 TAS folic acid metabolic process
GO:0055114 IEA oxidation-reduction process
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000021443 Mthfd1-201 protein_coding Mus_musculus 0 713

Loading

Warning (512): _cake_core_ cache was unable to write 'file_map' to File cache [CORE/Cake/Cache/Cache.php, line 323]
Warning (512): _cake_core_ cache was unable to write 'method_cache' to File cache [CORE/Cake/Cache/Cache.php, line 323]