C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: matrix metallopeptidase 12 (macrophage elastase)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000571244 MMP12-001 ENSG00000262406 9606 - 11:102862736-102875034 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBreastColonHeartLungMuscleOvaryPlacentaTestisENST00000571244
Transcript ID Adipose Adrenal Breast Colon Heart Lung Muscle Ovary Placenta Testis
ENST00000571244 0.063±0.00 2.236±0.00 0.656±0.00 0.414±0.30 0.093±0.00 0.407±0.09 0.039±0.00 1.427±1.03 4.262±2.21 0.054±0.02

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004175 TAS endopeptidase activity
GO:0004222 TAS:IEA metalloendopeptidase activity
GO:0005509 IEA calcium ion binding
GO:0005576 TAS extracellular region
GO:0005578 IEA proteinaceous extracellular matrix
GO:0006508 IEA proteolysis
GO:0008237 IEA metallopeptidase activity
GO:0008270 IEA zinc ion binding
GO:0022617 TAS extracellular matrix disassembly
GO:0030198 TAS extracellular matrix organization
GO:0030574 TAS collagen catabolic process
GO:0031012 IEA extracellular matrix
GO:0035313 IDA wound healing, spreading of epidermal cells
GO:0060054 IDA positive regulation of epithelial cell proliferation involved in wound healing

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000127722 Mmp12-002 nonsense_mediated_decay Mus_musculus 0 730
ENSMUST00000005950 Mmp12-001 protein_coding Mus_musculus 0 730
ENSMUST00000120655 Mmp12-003 protein_coding Mus_musculus 0 721
ENSMUST00000148005 Mmp12-005 retained_intron Mus_musculus 0 584
ENSMUST00000065079 Mmp12-004 protein_coding Mus_musculus 0 361

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