C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: matrix metallopeptidase 12 (macrophage elastase)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000262406 MMP12 9606 - 11:102862736-102875034 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000571244 MMP12-001 102862736-102875034 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBreastColonHeartLungMuscleOvaryPlacentaTestisENST00000571244
Transcript ID Adipose Adrenal Breast Colon Heart Lung Muscle Ovary Placenta Testis
ENST00000571244 0.063±0.00 2.236±0.00 0.656±0.00 0.414±0.30 0.093±0.00 0.407±0.09 0.039±0.00 1.427±1.03 4.262±2.21 0.054±0.02

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004175 TAS endopeptidase activity
GO:0004222 TAS:IEA metalloendopeptidase activity
GO:0005509 IEA calcium ion binding
GO:0005576 TAS extracellular region
GO:0005578 IEA proteinaceous extracellular matrix
GO:0006508 IEA proteolysis
GO:0008237 IEA metallopeptidase activity
GO:0008270 IEA zinc ion binding
GO:0022617 TAS extracellular matrix disassembly
GO:0030198 TAS extracellular matrix organization
GO:0030574 TAS collagen catabolic process
GO:0031012 IEA extracellular matrix
GO:0035313 IDA wound healing, spreading of epidermal cells
GO:0060054 IDA positive regulation of epithelial cell proliferation involved in wound healing

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000049723 Mmp12 matrix metallopeptidase 12 protein_coding Mus_musculus

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