C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: glycine receptor, beta
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000509282 GLRB-002 ENSG00000109738 9606 + 4:157076403-157170806 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLungMuscleOvaryPlacentaTestisENST00000509282
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Lung Muscle Ovary Placenta Testis
ENST00000509282 0.179±0.00 1.005±0.00 14.580±0.00 1.381±0.00 0.997±0.00 0.921±0.76 0.561±0.00 0.441±0.24 0.182±0.00 0.463±0.25 0.774±0.18 0.421±0.04

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006DW CIL_0006DW_0002 CGP 4:156760454-157172090
CIL_0006DX CIL_0006DX_0002 CGP 4:157076057-157366075

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001964 IMP startle response
GO:0005230 IEA extracellular ligand-gated ion channel activity
GO:0005515 IPI protein binding
GO:0005886 TAS plasma membrane
GO:0005887 NAS integral component of plasma membrane
GO:0006810 IEA transport
GO:0006811 IDA:IEA ion transport
GO:0007218 IDA neuropeptide signaling pathway
GO:0007268 IMP synaptic transmission
GO:0007399 IMP nervous system development
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0016594 IMP glycine binding
GO:0016933 IMP extracellular-glycine-gated ion channel activity
GO:0016934 TAS extracellular-glycine-gated chloride channel activity
GO:0030054 IEA cell junction
GO:0034220 TAS ion transmembrane transport
GO:0034707 IEA chloride channel complex
GO:0045211 IEA postsynaptic membrane
GO:0055085 TAS transmembrane transport
GO:1902476 IEA chloride transmembrane transport

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000029654 Glrb-001 protein_coding Mus_musculus 0 1842
ENSMUST00000135043 Glrb-004 nonsense_mediated_decay Mus_musculus 0 1816
ENSMUST00000107743 Glrb-003 protein_coding Mus_musculus 0 1077
ENSMUST00000132330 Glrb-002 nonsense_mediated_decay Mus_musculus 0 268
ENSDART00000005499 glra1-201 protein_coding Danio_rerio 3e-25 121
ENSDART00000066197 glra1-203 protein_coding Danio_rerio 5e-23 113
ENSDART00000047680 glra1-202 protein_coding Danio_rerio 5e-23 113
ENSDART00000136733 glra1-001 protein_coding Danio_rerio 5e-23 113

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