Institute of Cardiovascular Regeneration Webtool Repository

C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Accession	Transcript Name	Contained in Gene	Tax ID	Strand	Position	Biotype
Transcript Info
Description:	dual serine/threonine and tyrosine protein kinase
ENST00000367162	DSTYK-001	ENSG00000133059	9606	-	1:205142505-205211566	protein_coding

Expression Patterns

Transcript ID	Adipose	Adrenal	Brain	Breast	Colon	Heart	Kidney	Liver	Lung	Muscle	Ovary	Placenta	Testis
ENST00000367162	2.724±0.00	0.754±0.00	7.298±3.85	1.307±0.34	1.428±0.00	1.619±0.00	3.062±0.00	0.950±0.64	1.788±0.00	2.781±0.00	1.562±0.68	2.059±0.64	3.713±0.11

Conserved Regions
Gene is not located within a conserved region.

Gene Ontology
GO ID	Evidence Type	GO Description
GO:0004672	IEA	protein kinase activity
GO:0004674	IEA	protein serine/threonine kinase activity
GO:0004712	IEA	protein serine/threonine/tyrosine kinase activity
GO:0004713	IEA	protein tyrosine kinase activity
GO:0005524	IEA	ATP binding
GO:0005737	IDA	cytoplasm
GO:0006468	IEA	protein phosphorylation
GO:0016323	IDA	basolateral plasma membrane
GO:0016324	IDA	apical plasma membrane
GO:0016772	IEA	transferase activity, transferring phosphorus-containing groups
GO:0018108	IEA	peptidyl-tyrosine phosphorylation
GO:0033674	IMP	positive regulation of kinase activity
GO:0044344	IDA	cellular response to fibroblast growth factor stimulus
GO:0045743	IMP	positive regulation of fibroblast growth factor receptor signaling pathway
GO:0070374	IMP	positive regulation of ERK1 and ERK2 cascade

Homologs
ENSEMBL Accession	Gene Name	Biotype	Species	E-Value	Bit Score
ENSMUST00000045110	Dstyk-001	protein_coding	Mus_musculus	0	3554
ENSMUST00000188389	Dstyk-004	protein_coding	Mus_musculus	0	2976
ENSMUST00000187092	Dstyk-007	protein_coding	Mus_musculus	0	647
ENSMUST00000188006	Dstyk-005	retained_intron	Mus_musculus	0	601
ENSMUST00000191494	Dstyk-008	retained_intron	Mus_musculus	0	215

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