C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: dual serine/threonine and tyrosine protein kinase
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000045110 Dstyk-001 ENSMUSG00000042046 10090 + 1:132417555-132466958 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000045110
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000045110 7.175±1.63 4.174±0.68 9.597±0.46 5.891±0.85 5.613±0.53 3.385±0.37 4.238±0.35 7.258±0.63 2.896±0.89 10.277±1.21 2.987±0.20 8.348±1.39 4.209±2.18 1.642±0.71

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004674 IEA protein serine/threonine kinase activity
GO:0004712 IEA protein serine/threonine/tyrosine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005524 IEA ATP binding
GO:0005737 IDA cytoplasm
GO:0016323 IDA basolateral plasma membrane
GO:0016324 IDA apical plasma membrane
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0033674 ISS positive regulation of kinase activity
GO:0044344 ISS cellular response to fibroblast growth factor stimulus
GO:0045743 ISS positive regulation of fibroblast growth factor receptor signaling pathway
GO:0070374 ISS positive regulation of ERK1 and ERK2 cascade

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000367161 DSTYK-002 protein_coding Homo_sapiens 0 2983
ENST00000367162 DSTYK-001 protein_coding Homo_sapiens 0 3554
ENST00000615388 DSTYK-201 protein_coding Homo_sapiens 0 715

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