C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: polymerase (DNA directed), epsilon, catalytic subunit
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000320574 POLE-001 ENSG00000177084 9606 - 12:132623762-132687359 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000320574
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000320574 2.632±0.00 2.556±0.00 0.490±0.00 2.473±0.00 1.413±0.11 0.072±0.00 1.742±0.19 1.421±0.00 0.848±0.39 1.566±0.00 4.534±0.66 4.406±0.90 13.062±5.19

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000082 IMP G1/S transition of mitotic cell cycle
GO:0000166 IEA nucleotide binding
GO:0000278 TAS mitotic cell cycle
GO:0000722 TAS telomere maintenance via recombination
GO:0000723 TAS telomere maintenance
GO:0000731 IMP DNA synthesis involved in DNA repair
GO:0001701 IEA in utero embryonic development
GO:0003676 IEA nucleic acid binding
GO:0003677 IDA:IEA DNA binding
GO:0003682 IDA chromatin binding
GO:0003887 IMP:IEA DNA-directed DNA polymerase activity
GO:0005634 IDA:IEA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 IDA cytoplasm
GO:0005886 IDA plasma membrane
GO:0006260 IMP:IEA DNA replication
GO:0006270 TAS DNA replication initiation
GO:0006281 TAS DNA repair
GO:0006283 TAS transcription-coupled nucleotide-excision repair
GO:0006287 IDA base-excision repair, gap-filling
GO:0006289 TAS nucleotide-excision repair
GO:0006297 IMP nucleotide-excision repair, DNA gap filling
GO:0008270 IEA zinc ion binding
GO:0008622 IDA epsilon DNA polymerase complex
GO:0032201 TAS telomere maintenance via semi-conservative replication
GO:0051539 IEA 4 iron, 4 sulfur cluster binding
GO:0071897 IEA DNA biosynthetic process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000007296 Pole-001 protein_coding Mus_musculus 0 7380
ENSMUST00000131887 Pole-002 retained_intron Mus_musculus 0 2244
ENSMUST00000152495 Pole-004 retained_intron Mus_musculus 0 1496
ENSMUST00000112481 Pole-005 protein_coding Mus_musculus 0 1134
ENSDART00000081411 pole-001 protein_coding Danio_rerio 0 1072
ENSMUST00000141506 Pole-006 retained_intron Mus_musculus 0 870
ENSMUST00000112482 Pole-003 protein_coding Mus_musculus 0 614

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