C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: catenin (cadherin-associated protein), alpha 1, 102kDa
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000302763 CTNNA1-001 ENSG00000044115 9606 + 5:138753423-138935034 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000302763
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000302763 14.793±0.00 14.392±0.00 7.228±0.00 11.789±0.00 15.939±6.62 19.581±0.00 25.268±17.21 15.272±8.27 9.068±4.34 33.297±20.19 11.959±2.24 35.567±29.69 32.320±11.97 8.430±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005DA CIL_0005DA_0001 CGP 5:138554882-138935034
CIL_00062R CIL_00062R_0002 CGP 5:138610967-138935034

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001541 IEA ovarian follicle development
GO:0001669 IEA acrosomal vesicle
GO:0005198 IEA structural molecule activity
GO:0005515 IPI protein binding
GO:0005737 IEA cytoplasm
GO:0005829 TAS cytosol
GO:0005886 TAS plasma membrane
GO:0005911 IDA cell-cell junction
GO:0005912 IEA adherens junction
GO:0005913 IEA cell-cell adherens junction
GO:0005915 IEA zonula adherens
GO:0005925 IDA focal adhesion
GO:0007155 NAS:IEA cell adhesion
GO:0007163 IEA establishment or maintenance of cell polarity
GO:0007406 IEA negative regulation of neuroblast proliferation
GO:0007568 IEA aging
GO:0008013 IPI beta-catenin binding
GO:0008584 IEA male gonad development
GO:0014070 IEA response to organic cyclic compound
GO:0014704 IEA intercalated disc
GO:0015629 IEA actin cytoskeleton
GO:0016264 IEA gap junction assembly
GO:0016342 IDA catenin complex
GO:0017166 IPI vinculin binding
GO:0030027 IEA lamellipodium
GO:0031103 IEA axon regeneration
GO:0034329 TAS cell junction assembly
GO:0034332 TAS adherens junction organization
GO:0034613 IEA cellular protein localization
GO:0042127 IEA regulation of cell proliferation
GO:0042475 IEA odontogenesis of dentin-containing tooth
GO:0042692 TAS muscle cell differentiation
GO:0043066 IEA negative regulation of apoptotic process
GO:0043297 NAS apical junction assembly
GO:0043627 IEA response to estrogen
GO:0044822 IDA poly(A) RNA binding
GO:0045216 TAS cell-cell junction organization
GO:0045295 IPI gamma-catenin binding
GO:0045296 IEA:IPI cadherin binding
GO:0045880 IEA positive regulation of smoothened signaling pathway
GO:0051015 IEA actin filament binding
GO:0051149 TAS positive regulation of muscle cell differentiation
GO:0051291 IEA protein heterooligomerization
GO:0071681 IDA cellular response to indole-3-methanol
GO:0090136 IEA epithelial cell-cell adhesion
GO:2000146 IEA negative regulation of cell motility
GO:2001045 IEA negative regulation of integrin-mediated signaling pathway
GO:2001240 IEA negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
GO:2001241 IEA positive regulation of extrinsic apoptotic signaling pathway in absence of ligand

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000042345 Ctnna1-201 protein_coding Mus_musculus 0 3862
ENSMUST00000075340 Ctnna2-201 protein_coding Mus_musculus 0 1131
ENSMUST00000161846 Ctnna2-001 protein_coding Mus_musculus 0 1131
ENSDART00000101306 ctnna2-002 protein_coding Danio_rerio 0 1088
ENSMUST00000159626 Ctnna2-003 protein_coding Mus_musculus 0 1027
ENSMUST00000160894 Ctnna2-002 protein_coding Mus_musculus 0 1027
ENSDART00000153506 ctnna2-202 protein_coding Danio_rerio 0 793

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