C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: cholinergic receptor, nicotinic, beta 4 (neuronal)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000261751 CHRNB4-001 ENSG00000117971 9606 - 15:78624119-78641245 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalColonOvaryTestisENST00000261751
Transcript ID Adrenal Colon Ovary Testis
ENST00000261751 1.523±0.00 0.454±0.05 0.112±0.04 2.498±1.86

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001KZ CIL_0001KZ_0001 CGP 15:78593052-78727754

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001508 IEA action potential
GO:0004889 TAS acetylcholine-activated cation-selective channel activity
GO:0005230 IEA extracellular ligand-gated ion channel activity
GO:0005886 TAS plasma membrane
GO:0005887 IC integral component of plasma membrane
GO:0005892 TAS acetylcholine-gated channel complex
GO:0006810 IEA transport
GO:0006811 TAS:IEA ion transport
GO:0006812 TAS cation transport
GO:0006939 IEA smooth muscle contraction
GO:0006940 IEA regulation of smooth muscle contraction
GO:0007165 IDA signal transduction
GO:0007268 TAS synaptic transmission
GO:0007271 TAS synaptic transmission, cholinergic
GO:0007626 IEA locomotory behavior
GO:0015276 TAS ligand-gated ion channel activity
GO:0015464 IDA acetylcholine receptor activity
GO:0016020 IEA membrane
GO:0016021 NAS:IEA integral component of membrane
GO:0030054 IEA cell junction
GO:0034220 TAS ion transmembrane transport
GO:0035094 IEA response to nicotine
GO:0035095 IEA behavioral response to nicotine
GO:0042391 IEA regulation of membrane potential
GO:0045211 IEA postsynaptic membrane
GO:0046928 NAS regulation of neurotransmitter secretion
GO:0060084 IMP synaptic transmission involved in micturition
GO:0098655 IEA cation transmembrane transport

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000034854 Chrnb4-201 protein_coding Mus_musculus 0 1539
ENSMUST00000029562 Chrnb2-201 protein_coding Mus_musculus 0 616
ENSDART00000008870 CHRNB4-201 protein_coding Danio_rerio 0 601
ENSDART00000079613 chrna2b-201 protein_coding Danio_rerio 3e-27 128
ENSDART00000136317 chrna2b-001 protein_coding Danio_rerio 3e-27 128

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