C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: cholinergic receptor, nicotinic, alpha polypeptide 2b (neuronal)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSDART00000136317 chrna2b-001 ENSDARG00000057025 7955 + 20:19865780-19896675 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainKidneyMuscleENSDART00000136317
Transcript ID Brain Kidney Muscle
ENSDART00000136317 1.470±1.10 0.236±0.16 0.065±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000OS CIL_0000OS_0002 CGP 20:19865780-19936291

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004889 IEA acetylcholine-activated cation-selective channel activity
GO:0005216 IEA ion channel activity
GO:0005230 IEA extracellular ligand-gated ion channel activity
GO:0005886 IEA plasma membrane
GO:0006810 IEA transport
GO:0006811 IEA ion transport
GO:0016020 IEA membrane
GO:0016021 IEA integral to membrane
GO:0030054 IEA cell junction
GO:0045202 IEA synapse
GO:0045211 IEA postsynaptic membrane

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000022620 Chrna2-001 protein_coding Mus_musculus 0 688
ENSMUST00000029562 Chrnb2-201 protein_coding Mus_musculus 2e-36 159
ENSMUST00000033882 Chrna6-201 protein_coding Mus_musculus 0 211
ENST00000240132 CHRNA2-004 protein_coding Homo_sapiens 0 699
ENST00000261751 CHRNB4-001 protein_coding Homo_sapiens 3e-27 128
ENST00000326828 CHRNA3-001 protein_coding Homo_sapiens 0 307
ENST00000348639 CHRNA3-002 protein_coding Homo_sapiens 0 307
ENST00000368476 CHRNB2-001 protein_coding Homo_sapiens 5e-33 148
ENST00000370263 CHRNA4-001 protein_coding Homo_sapiens 0 604
ENST00000407991 CHRNA2-201 protein_coding Homo_sapiens 0 726
ENST00000463705 CHRNA4-002 processed_transcript Homo_sapiens 0 501
ENST00000467563 CHRNA4-004 processed_transcript Homo_sapiens 0 538
ENST00000498043 CHRNA4-007 nonsense_mediated_decay Homo_sapiens 0 501
ENST00000520933 CHRNA2-001 protein_coding Homo_sapiens 0 726
ENST00000523529 CHRNA2-006 retained_intron Homo_sapiens 0 726
ENST00000523695 CHRNA2-005 nonsense_mediated_decay Homo_sapiens 0 472
ENST00000558903 CHRNA3-008 processed_transcript Homo_sapiens 0 217
ENST00000559658 CHRNA3-003 nonsense_mediated_decay Homo_sapiens 0 307
ENST00000559849 CHRNB4-002 nonsense_mediated_decay Homo_sapiens 4e-25 121
ENST00000615287 CHRNA4-201 protein_coding Homo_sapiens 0 501

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