C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: glutamate receptor, metabotropic 7
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000172951 Grm7-001 ENSMUSG00000056755 10090 + 6:110645582-111567230 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainColonHeartKidneyLiverLungOvaryPlacentaTestisENSMUST00000172951
Transcript ID Adipose Adrenal Bladder Brain Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENSMUST00000172951 0.022±0.00 0.234±0.08 0.069±0.02 4.984±1.35 0.125±0.01 0.028±0.02 0.254±0.00 0.011±0.00 0.019±0.00 0.355±0.13 0.011±0.00 0.083±0.04

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005RO CIL_0005RO_0002 CGP 6:108828641-111567230
CIL_0003AB CIL_0003AB_0002 CGP 6:110645581-112330425

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001642 ISS group III metabotropic glutamate receptor activity
GO:0001661 IMP conditioned taste aversion
GO:0001662 IMP behavioral fear response
GO:0005245 IDA voltage-gated calcium channel activity
GO:0005246 IDA calcium channel regulator activity
GO:0005509 IEA calcium ion binding
GO:0005887 IBA integral component of plasma membrane
GO:0005938 IEA cell cortex
GO:0007194 IEA negative regulation of adenylate cyclase activity
GO:0007196 ISS adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway
GO:0007268 IDA synaptic transmission
GO:0007605 IEA sensory perception of sound
GO:0007608 IEA sensory perception of smell
GO:0007613 IMP memory
GO:0007614 IMP short-term memory
GO:0008066 ISS glutamate receptor activity
GO:0008306 IMP associative learning
GO:0010855 IEA adenylate cyclase inhibitor activity
GO:0016595 IEA glutamate binding
GO:0019226 IMP transmission of nerve impulse
GO:0030165 TAS PDZ domain binding
GO:0030425 IEA dendrite
GO:0030534 IMP adult behavior
GO:0030818 IEA negative regulation of cAMP biosynthetic process
GO:0031279 IEA regulation of cyclase activity
GO:0033555 IMP multicellular organismal response to stress
GO:0042734 IDA presynaptic membrane
GO:0043235 ISO receptor complex
GO:0048787 TAS presynaptic active zone membrane
GO:0050877 IMP neurological system process
GO:0051966 IBA regulation of synaptic transmission, glutamatergic
GO:0070588 IDA calcium ion transmembrane transport
GO:0070905 IEA serine binding
GO:1901214 TAS regulation of neuron death

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000357716 GRM7-001 protein_coding Homo_sapiens 0 5057
ENST00000389335 GRM7-004 nonsense_mediated_decay Homo_sapiens 0 3812
ENST00000389336 GRM7-003 protein_coding Homo_sapiens 0 3814
ENST00000402647 GRM7-201 protein_coding Homo_sapiens 0 2922
ENST00000435689 GRM7-007 nonsense_mediated_decay Homo_sapiens 0 712
ENST00000440923 GRM7-002 nonsense_mediated_decay Homo_sapiens 0 3812
ENST00000443259 GRM7-011 nonsense_mediated_decay Homo_sapiens 0 263
ENST00000445087 GRM7-009 protein_coding Homo_sapiens 0 665
ENST00000448328 GRM7-012 protein_coding Homo_sapiens 0 675
ENST00000458641 GRM7-005 processed_transcript Homo_sapiens 0 1206
ENST00000461677 GRM7-008 retained_intron Homo_sapiens 0 645
ENST00000463676 GRM7-006 retained_intron Homo_sapiens 0 2647
ENST00000467425 GRM7-013 nonsense_mediated_decay Homo_sapiens 0 3855
ENST00000486284 GRM7-015 protein_coding Homo_sapiens 0 3855

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