C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: glutamate receptor, metabotropic 7
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000056755 Grm7 10090 + 6:110645581-111567230 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000071076 Grm7-003 110645581-111566067 protein_coding
  ENSMUST00000172951 Grm7-001 110645582-111567230 protein_coding
  ENSMUST00000173001 Grm7-004 111495715-111499933 protein_coding
  ENSMUST00000174018 Grm7-002 110645581-111497090 nonsense_mediated_decay
  ENSMUST00000174310 Grm7-005 111495744-111502284 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENSMUST00000071076ENSMUST00000172951ENSMUST00000174018
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENSMUST00000071076 0.364±0.04 0.241±0.07 0.106±0.00 4.895±0.00 0.034±0.01 0.174±0.07 0.084±0.03 0.243±0.20 0.016±0.01 0.012±0.00 0.709±0.37 0.015±0.00 0.172±0.11
ENSMUST00000172951 0.022±0.00 0.234±0.08 0.069±0.02 4.984±1.35 N/A 0.125±0.01 0.028±0.02 0.254±0.00 0.011±0.00 0.019±0.00 0.355±0.13 0.011±0.00 0.083±0.04
ENSMUST00000174018 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.416±0.00 N/A 0.021±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005RO CIL_0005RO_0002 CGP 6:108828641-111567230
CIL_0003AB CIL_0003AB_0002 CGP 6:110645581-112330425

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001642 IBA group III metabotropic glutamate receptor activity
GO:0001661 IMP conditioned taste aversion
GO:0001662 IMP behavioral fear response
GO:0005245 IDA voltage-gated calcium channel activity
GO:0005246 IDA calcium channel regulator activity
GO:0005509 IEA calcium ion binding
GO:0005887 IBA integral component of plasma membrane
GO:0005938 IEA cell cortex
GO:0007194 IEA negative regulation of adenylate cyclase activity
GO:0007196 IBA adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway
GO:0007268 IDA synaptic transmission
GO:0007605 IEA sensory perception of sound
GO:0007608 IEA sensory perception of smell
GO:0007613 IMP memory
GO:0007614 IMP short-term memory
GO:0008066 ISS glutamate receptor activity
GO:0008306 IMP associative learning
GO:0010855 IEA adenylate cyclase inhibitor activity
GO:0016595 IEA glutamate binding
GO:0019226 IMP transmission of nerve impulse
GO:0030165 TAS PDZ domain binding
GO:0030425 IEA dendrite
GO:0030534 IMP adult behavior
GO:0030818 IEA negative regulation of cAMP biosynthetic process
GO:0031279 IEA regulation of cyclase activity
GO:0033555 IMP multicellular organismal response to stress
GO:0042734 IDA presynaptic membrane
GO:0043235 ISO receptor complex
GO:0048787 TAS presynaptic active zone membrane
GO:0050877 IMP neurological system process
GO:0051966 IBA regulation of synaptic transmission, glutamatergic
GO:0070588 IDA calcium ion transmembrane transport
GO:0070905 IEA serine binding
GO:1901214 TAS regulation of neuron death

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000196277 GRM7 glutamate receptor, metabotropic 7 protein_coding Homo_sapiens

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