C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: protein kinase C, alpha
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000100302 Prkca-004 ENSMUSG00000050965 10090 - 11:107938177-107979639 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; HeartOvaryPlacentaENSMUST00000100302
Transcript ID Heart Ovary Placenta
ENSMUST00000100302 2.930±0.44 1.554±0.00 1.095±0.56

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000188 IMP inactivation of MAPK activity
GO:0001750 IDA photoreceptor outer segment
GO:0001933 IMP negative regulation of protein phosphorylation
GO:0001934 IMP positive regulation of protein phosphorylation
GO:0002026 IMP regulation of the force of heart contraction
GO:0002062 IDA chondrocyte differentiation
GO:0004674 IDA protein serine/threonine kinase activity
GO:0004697 IDA protein kinase C activity
GO:0004698 IDA calcium-dependent protein kinase C activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005739 IDA mitochondrion
GO:0005886 IDA plasma membrane
GO:0006468 IDA protein phosphorylation
GO:0006469 IMP negative regulation of protein kinase activity
GO:0006874 IMP cellular calcium ion homeostasis
GO:0006937 IMP regulation of muscle contraction
GO:0008285 IGI negative regulation of cell proliferation
GO:0030425 IDA dendrite
GO:0030593 IMP neutrophil chemotaxis
GO:0036289 IDA peptidyl-serine autophosphorylation
GO:0043025 IDA neuronal cell body
GO:0045177 IDA apical part of cell
GO:0046325 IMP negative regulation of glucose import
GO:0046627 IMP negative regulation of insulin receptor signaling pathway
GO:0050729 IMP positive regulation of inflammatory response
GO:0050730 IMP regulation of peptidyl-tyrosine phosphorylation
GO:0050930 IMP induction of positive chemotaxis
GO:0071322 IDA cellular response to carbohydrate stimulus
GO:0097193 IMP intrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000284384 PRKCA-003 nonsense_mediated_decay Homo_sapiens 0 324
ENST00000413366 PRKCA-002 protein_coding Homo_sapiens 0 1535

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