C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: serine/arginine-rich splicing factor 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000136450 SRSF1 9606 - 17:58003360-58007346 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000258962 SRSF1-001 58004849-58007346 protein_coding
  ENST00000578430 SRSF1-007 58006242-58007346 retained_intron
  ENST00000581497 SRSF1-009 58003493-58005134 processed_transcript
  ENST00000581979 SRSF1-004 58003807-58007232 nonsense_mediated_decay
  ENST00000582730 SRSF1-003 58003360-58007261 protein_coding
  ENST00000583741 SRSF1-005 58004849-58007261 nonsense_mediated_decay
  ENST00000584668 SRSF1-008 58003802-58006405 nonsense_mediated_decay
  ENST00000584773 SRSF1-002 58004588-58007261 protein_coding
  ENST00000585096 SRSF1-006 58004822-58007273 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000258962ENST00000581497ENST00000581979ENST00000582730ENST00000584668ENST00000584773
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000258962 N/A N/A N/A N/A N/A 25.378±0.00 N/A 12.962±0.00 N/A 12.269±0.00 7.126±0.00 31.974±13.07 33.191±0.00 38.167±0.00
ENST00000581497 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 13.602±0.00 N/A N/A N/A
ENST00000581979 N/A N/A N/A N/A N/A N/A 4.655±0.00 N/A 14.002±0.00 N/A N/A N/A N/A N/A
ENST00000582730 8.993±0.00 21.904±0.00 6.289±0.00 13.608±0.00 13.201±4.83 20.168±0.34 8.080±5.14 17.747±11.91 10.739±0.00 15.760±0.12 2.117±0.00 32.773±10.79 23.260±5.76 26.467±2.98
ENST00000584668 N/A 33.260±0.00 N/A N/A 27.532±0.00 26.603±0.00 N/A 42.232±0.00 N/A 28.600±0.00 N/A 56.628±6.16 23.840±0.00 43.724±8.69
ENST00000584773 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 4.432±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007PL CIL_0007PL_0001 UCNEbase 17:57406597-58005077
CIL_0009DM CIL_0009DM_0001 VISTA 17:57461902-58063720
CIL_0009DL CIL_0009DL_0001 VISTA 17:57574410-58175690

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000166 IEA nucleotide binding
GO:0000395 IDA mRNA 5'-splice site recognition
GO:0000398 IC mRNA splicing, via spliceosome
GO:0001701 IEA in utero embryonic development
GO:0003676 IEA nucleic acid binding
GO:0003723 IDA RNA binding
GO:0003729 IDA mRNA binding
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 IDA nucleoplasm
GO:0005737 IEA cytoplasm
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006366 TAS transcription from RNA polymerase II promoter
GO:0006369 TAS termination of RNA polymerase II transcription
GO:0006376 TAS mRNA splice site selection
GO:0006397 TAS mRNA processing
GO:0006406 TAS mRNA export from nucleus
GO:0006417 IEA regulation of translation
GO:0008380 TAS RNA splicing
GO:0010467 TAS gene expression
GO:0016607 IDA nuclear speck
GO:0031124 TAS mRNA 3'-end processing
GO:0035145 IDA exon-exon junction complex
GO:0043488 IEA regulation of mRNA stability
GO:0044822 IDA poly(A) RNA binding
GO:0048024 IEA regulation of mRNA splicing, via spliceosome
GO:0050733 IEA RS domain binding
GO:0060048 IEA cardiac muscle contraction
GO:0070062 IDA extracellular vesicular exosome
GO:0071013 IDA catalytic step 2 spliceosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000017843 srsf1b serine/arginine-rich splicing factor 1b protein_coding Danio_rerio
ENSMUSG00000018379 Srsf1 serine/arginine-rich splicing factor 1 protein_coding Mus_musculus

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