C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: complement factor B
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000425368 CFB-001 ENSG00000243649 9606 + 6:31945709-31952084 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderColonKidneyLiverMuscleOvaryTestisENST00000425368
Transcript ID Bladder Colon Kidney Liver Muscle Ovary Testis
ENST00000425368 0.843±0.00 3.290±0.00 143.854±123.32 253.908±252.71 0.664±0.00 17.818±0.00 5.506±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000421 CIL_000421_0001 CGP 6:31897785-31945672
CIL_0001PM CIL_0001PM_0003 CGP 6:31927698-31952084

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001848 TAS complement binding
GO:0003824 IEA catalytic activity
GO:0004252 TAS:IEA serine-type endopeptidase activity
GO:0005576 TAS:IEA extracellular region
GO:0005615 IDA extracellular space
GO:0005886 TAS plasma membrane
GO:0006508 IEA proteolysis
GO:0006956 TAS:IEA complement activation
GO:0006957 NAS complement activation, alternative pathway
GO:0030449 TAS regulation of complement activation
GO:0045087 TAS innate immune response
GO:0070062 IDA extracellular vesicular exosome
GO:0072562 IDA blood microparticle

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000025229 Cfb-201 protein_coding Mus_musculus 0 2211
ENSMUST00000128767 Cfb-001 protein_coding Mus_musculus 0 2211
ENSMUST00000176203 Cfb-202 protein_coding Mus_musculus 0 2185
ENSMUST00000154526 Cfb-002 protein_coding Mus_musculus 0 2185
ENSMUST00000146299 Gm20547-001 protein_coding Mus_musculus 0 2185
ENSMUST00000129891 Gm20547-002 protein_coding Mus_musculus 0 1956

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