C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: myosin light chain kinase 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000375985 MYLK2-001 ENSG00000101306 9606 + 20:31819373-31834689 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BreastHeartLiverLungMuscleOvaryTestisENST00000375985
Transcript ID Breast Heart Liver Lung Muscle Ovary Testis
ENST00000375985 5.183±5.04 0.018±0.00 0.036±0.00 0.141±0.00 120.986±84.98 0.111±0.08 0.262±0.08

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008K5 CIL_0008K5_0001 VISTA 20:31303913-31904751
CIL_00089Z CIL_00089Z_0001 VISTA 20:31373735-31977079
CIL_0008N4 CIL_0008N4_0001 VISTA 20:31410024-32010895
CIL_000319 CIL_000319_0002 CGP 20:31739271-31834689
CIL_0000JB CIL_0000JB_0001 CGP 20:31819308-31845619

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004672 IEA protein kinase activity
GO:0004683 ISS calmodulin-dependent protein kinase activity
GO:0004687 ISS myosin light chain kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005515 IPI protein binding
GO:0005516 ISS calmodulin binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0006468 IEA protein phosphorylation
GO:0006941 IDA striated muscle contraction
GO:0010628 IDA positive regulation of gene expression
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0018107 IDA peptidyl-threonine phosphorylation
GO:0030017 IC sarcomere
GO:0032971 IDA regulation of muscle filament sliding
GO:0035914 IDA skeletal muscle cell differentiation
GO:0046777 IDA protein autophosphorylation
GO:0055008 IMP cardiac muscle tissue morphogenesis
GO:0060048 IC cardiac muscle contraction

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000028970 Mylk2-001 protein_coding Mus_musculus 0 1849

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