C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: MKL/myocardin-like 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000318282 MKL2-201 ENSG00000186260 9606 + 16:14079288-14266772 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBreastMuscleOvaryPlacentaTestisENST00000318282
Transcript ID Adrenal Breast Muscle Ovary Placenta Testis
ENST00000318282 1.568±0.00 1.552±0.00 2.047±0.00 0.763±0.04 0.824±0.00 1.646±0.64

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002RP CIL_0002RP_0002 CGP 16:13920157-14266773
CIL_0007DW CIL_0007DW_0001 CGP 16:14071321-14632728

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001701 IEA in utero embryonic development
GO:0001889 IEA liver development
GO:0003007 IEA heart morphogenesis
GO:0003676 IEA nucleic acid binding
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0003713 IDA transcription coactivator activity
GO:0003779 IEA actin binding
GO:0005515 IPI protein binding
GO:0005634 IC nucleus
GO:0005737 IEA cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0007507 IEA heart development
GO:0007517 IEA muscle organ development
GO:0010467 IEA gene expression
GO:0010468 IEA regulation of gene expression
GO:0045844 IDA positive regulation of striated muscle tissue development
GO:0045893 IEA positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0048514 IEA blood vessel morphogenesis
GO:0048568 IEA embryonic organ development
GO:0048738 IEA cardiac muscle tissue development
GO:0051145 IEA smooth muscle cell differentiation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000009713 Mkl2-003 protein_coding Mus_musculus 0 1269
ENSMUST00000149359 Mkl2-001 protein_coding Mus_musculus 0 1079
ENSMUST00000056715 Mkl2-201 protein_coding Mus_musculus 0 193
ENSMUST00000115809 Mkl2-004 protein_coding Mus_musculus 0 193
ENSDART00000112456 MKL2 (1 of 3)-201 protein_coding Danio_rerio 1e-20 108
ENSDART00000127655 mkl2a-201 protein_coding Danio_rerio 1e-20 108
ENSDART00000153177 mkl2a-001 protein_coding Danio_rerio 1e-20 108

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