C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: actin related protein 2/3 complex, subunit 2, 34kDa
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000295685 ARPC2-001 ENSG00000163466 9606 + 2:218217210-218254356 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBrainOvaryPlacentaTestisENST00000295685
Transcript ID Bladder Brain Ovary Placenta Testis
ENST00000295685 4.734±0.00 5.825±0.00 35.842±0.00 95.530±0.00 57.043±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007WL CIL_0007WL_0001 VISTA 2:217636448-218238840
CIL_0005VM CIL_0005VM_0001 CGP 2:218162845-218254356
CIL_0005VL CIL_0005VL_0001 CGP 2:218217094-218263859

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005200 IDA structural constituent of cytoskeleton
GO:0005515 IPI protein binding
GO:0005737 IDA cytoplasm
GO:0005768 IEA endosome
GO:0005794 IDA Golgi apparatus
GO:0005829 TAS cytosol
GO:0005856 IEA cytoskeleton
GO:0005885 IDA:IEA Arp2/3 protein complex
GO:0005886 IEA plasma membrane
GO:0005925 IDA focal adhesion
GO:0006928 TAS cellular component movement
GO:0010592 IMP positive regulation of lamellipodium assembly
GO:0015629 TAS:IEA actin cytoskeleton
GO:0019894 IEA kinesin binding
GO:0030833 IEA regulation of actin filament polymerization
GO:0030838 IEA positive regulation of actin filament polymerization
GO:0031252 IEA cell leading edge
GO:0034314 IDA:IEA Arp2/3 complex-mediated actin nucleation
GO:0035650 IEA AP-1 adaptor complex binding
GO:0038096 TAS Fc-gamma receptor signaling pathway involved in phagocytosis
GO:0043005 IEA neuron projection
GO:0045087 TAS innate immune response
GO:0045202 IEA synapse
GO:0051015 IDA actin filament binding
GO:0070062 IDA extracellular vesicular exosome
GO:0071933 IEA Arp2/3 complex binding
GO:1900026 IEA positive regulation of substrate adhesion-dependent cell spreading

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000113820 Arpc2-001 protein_coding Mus_musculus 0 1888
ENSMUST00000006467 Arpc2-002 protein_coding Mus_musculus 0 1801
ENSMUST00000113819 Arpc2-003 protein_coding Mus_musculus 0 1452
ENSMUST00000185733 Arpc2-004 protein_coding Mus_musculus 3e-30 137

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