C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: early growth response 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000165033 Egr1-201 ENSMUSG00000038418 10090 + 18:34861207-34864956 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000165033
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000165033 7.333±0.94 5.372±0.86 6.667±2.29 6.173±7.15 17.245±7.91 6.925±2.39 5.407±0.53 1.896±0.24 2.396±1.23 7.883±3.02 1.021±0.17 23.761±15.33 0.925±0.44 1.954±1.26

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005DD CIL_0005DD_0002 CGP 18:34840589-34864984
CIL_0005DC CIL_0005DC_0002 CGP 18:34859823-34932007

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0000977 IMP RNA polymerase II regulatory region sequence-specific DNA binding
GO:0000982 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity
GO:0001077 IMP RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0005634 ISS nucleus
GO:0005737 ISS cytoplasm
GO:0006355 IMP regulation of transcription, DNA-templated
GO:0009749 IDA response to glucose
GO:0030217 IMP T cell differentiation
GO:0030509 IDA BMP signaling pathway
GO:0032868 IDA response to insulin
GO:0035914 IMP skeletal muscle cell differentiation
GO:0043066 IBA negative regulation of apoptotic process
GO:0044212 IDA transcription regulatory region DNA binding
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046872 IEA metal ion binding
GO:0048169 IBA regulation of long-term neuronal synaptic plasticity
GO:0071310 IDA cellular response to organic substance
GO:0071320 IBA cellular response to cAMP
GO:0071371 IBA cellular response to gonadotropin stimulus
GO:0071480 IMP cellular response to gamma radiation
GO:0071504 ISS cellular response to heparin
GO:0071506 ISS cellular response to mycophenolic acid
GO:0072110 ISS glomerular mesangial cell proliferation
GO:0072303 ISS positive regulation of glomerular metanephric mesangial cell proliferation
GO:0090090 IMP negative regulation of canonical Wnt signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000239938 EGR1-001 protein_coding Homo_sapiens 0 2998

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