C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000056795 serpine1 7955 - 7:27391452-27395882 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000079347 serpine1-001 27391452-27395882 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000079347
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000079347 1.977±1.34 34.651±30.03 53.547±30.82 2.055±0.00 25.401±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005LE CIL_0005LE_0001 CGP 7:27370930-27395882

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004867 IDA serine-type endopeptidase inhibitor activity
GO:0005576 IEA extracellular region
GO:0005615 IEA extracellular space
GO:0006955 IEA immune response
GO:0008009 IEA chemokine activity
GO:0010757 IDA negative regulation of plasminogen activation
GO:0010951 IDA negative regulation of endopeptidase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000106366 SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 protein_coding Homo_sapiens
ENSMUSG00000037411 Serpine1 serine (or cysteine) peptidase inhibitor, clade E, member 1 protein_coding Mus_musculus

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