C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: NK2 homeobox 6
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000044186 Nkx2-6 10090 + 14:69171802-69175518 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000062437 Nkx2-6-001 69171802-69175518 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBreastKidneyLiverOvaryPlacentaTestisENSMUST00000062437
Transcript ID Adipose Breast Kidney Liver Ovary Placenta Testis
ENSMUST00000062437 0.026±0.00 0.025±0.00 0.068±0.03 0.403±0.21 0.104±0.03 0.136±0.17 31.084±8.61

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006NB CIL_0006NB_0002 CGP 14:69029289-69175518
CIL_0005R4 CIL_0005R4_0002 CGP 14:69171802-69194662

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0005575 ND cellular_component
GO:0005634 IEA nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0007507 IGI heart development
GO:0008284 IGI positive regulation of cell proliferation
GO:0021854 IEP hypothalamus development
GO:0030154 IGI cell differentiation
GO:0035050 IEP embryonic heart tube development
GO:0043066 IGI negative regulation of apoptotic process
GO:0043565 IEA sequence-specific DNA binding
GO:0043586 IEP tongue development
GO:0048565 IEP digestive tract development
GO:0055014 IEP atrial cardiac muscle cell development
GO:0055015 IEP ventricular cardiac muscle cell development
GO:0060037 IGI pharyngeal system development
GO:0060039 IEP pericardium development

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000021232 nkx2.7 NK2 transcription factor related 7 protein_coding Danio_rerio
ENSG00000180053 NKX2-6 NK2 homeobox 6 protein_coding Homo_sapiens

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