C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: NK6 homeobox 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000041309 Nkx6-2 10090 - 7:139579376-139582797 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000097974 Nkx6-2-002 139579376-139582797 nonsense_mediated_decay
  ENSMUST00000106095 Nkx6-2-001 139581220-139582790 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainTestisENSMUST00000097974ENSMUST00000106095
Transcript ID Brain Testis
ENSMUST00000097974 6.762±5.14 N/A
ENSMUST00000106095 N/A 9.053±1.15

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000BD CIL_0000BD_0002 CGP 7:139389109-139582797

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0005634 IDA nucleus
GO:0010454 IMP negative regulation of cell fate commitment
GO:0010455 IMP positive regulation of cell fate commitment
GO:0021912 IGI regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification
GO:0021913 IMP regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification
GO:0022010 IMP central nervous system myelination
GO:0030154 IGI cell differentiation
GO:0031018 IGI endocrine pancreas development
GO:0043565 IDA sequence-specific DNA binding
GO:0045686 IGI negative regulation of glial cell differentiation
GO:0045687 IGI positive regulation of glial cell differentiation
GO:0048709 IGI oligodendrocyte differentiation
GO:0050885 IMP neuromuscular process controlling balance

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000044075 nkx6.2 NK6 homeobox 2 protein_coding Danio_rerio
ENSG00000148826 NKX6-2 NK6 homeobox 2 protein_coding Homo_sapiens

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