C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: wingless-type MMTV integration site family, member 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000036856 Wnt4 10090 + 4:137277489-137299726 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000045747 Wnt4-001 137277489-137299726 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000045747
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000045747 2.712±2.51 53.878±7.61 12.483±0.22 2.211±1.29 4.001±1.05 3.049±0.61 0.141±0.08 1.371±0.37 0.723±0.67 4.780±1.16 5.235±1.55 24.438±5.66 2.170±1.48 0.262±0.17

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001656 IMP metanephros development
GO:0001658 IMP branching involved in ureteric bud morphogenesis
GO:0001822 IEA kidney development
GO:0001823 IMP mesonephros development
GO:0001837 IEA epithelial to mesenchymal transition
GO:0001838 IDA embryonic epithelial tube formation
GO:0001889 IEA liver development
GO:0003714 IDA transcription corepressor activity
GO:0005102 TAS receptor binding
GO:0005109 IPI frizzled binding
GO:0005515 IPI protein binding
GO:0005578 IEA proteinaceous extracellular matrix
GO:0005615 ISS extracellular space
GO:0005737 ISS cytoplasm
GO:0005788 TAS endoplasmic reticulum lumen
GO:0006702 ISS androgen biosynthetic process
GO:0007165 TAS signal transduction
GO:0007267 TAS cell-cell signaling
GO:0007276 IGI gamete generation
GO:0007548 IMP sex differentiation
GO:0008584 ISS male gonad development
GO:0008585 IMP female gonad development
GO:0009267 IEP cellular response to starvation
GO:0009986 IDA cell surface
GO:0010629 ISS negative regulation of gene expression
GO:0010894 ISS negative regulation of steroid biosynthetic process
GO:0018345 ISS protein palmitoylation
GO:0022407 IMP regulation of cell-cell adhesion
GO:0030154 IMP cell differentiation
GO:0030182 IBA neuron differentiation
GO:0030237 ISS female sex determination
GO:0030325 IEA adrenal gland development
GO:0030336 IGI negative regulation of cell migration
GO:0030501 ISS positive regulation of bone mineralization
GO:0031012 IDA extracellular matrix
GO:0032321 IGI positive regulation of Rho GTPase activity
GO:0032349 ISS positive regulation of aldosterone biosynthetic process
GO:0032967 ISS positive regulation of collagen biosynthetic process
GO:0033077 IDA T cell differentiation in thymus
GO:0033080 IMP immature T cell proliferation in thymus
GO:0035239 IMP tube morphogenesis
GO:0035567 IDA non-canonical Wnt signaling pathway
GO:0038030 IEA non-canonical Wnt signaling pathway via MAPK cascade
GO:0040037 IGI negative regulation of fibroblast growth factor receptor signaling pathway
GO:0042445 IMP hormone metabolic process
GO:0045165 IMP cell fate commitment
GO:0045596 IMP negative regulation of cell differentiation
GO:0045669 ISS positive regulation of osteoblast differentiation
GO:0045836 IGI positive regulation of meiosis
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0045893 ISS positive regulation of transcription, DNA-templated
GO:0048599 IGI oocyte development
GO:0048754 IGI branching morphogenesis of an epithelial tube
GO:0048856 IGI anatomical structure development
GO:0051145 IDA smooth muscle cell differentiation
GO:0051496 IGI positive regulation of stress fiber assembly
GO:0051894 IGI positive regulation of focal adhesion assembly
GO:0060070 ISS canonical Wnt signaling pathway
GO:0060126 IMP somatotropin secreting cell differentiation
GO:0060129 IMP thyroid-stimulating hormone-secreting cell differentiation
GO:0060231 IMP mesenchymal to epithelial transition
GO:0060748 IMP tertiary branching involved in mammary gland duct morphogenesis
GO:0060993 IGI kidney morphogenesis
GO:0061045 IGI negative regulation of wound healing
GO:0061180 IEA mammary gland epithelium development
GO:0061184 ISS positive regulation of dermatome development
GO:0061205 ISS paramesonephric duct development
GO:0061369 IEA negative regulation of testicular blood vessel morphogenesis
GO:0071560 IEA cellular response to transforming growth factor beta stimulus
GO:0072033 IMP renal vesicle formation
GO:0072034 IDA renal vesicle induction
GO:0072162 NAS metanephric mesenchymal cell differentiation
GO:0072164 IGI mesonephric tubule development
GO:0072174 IMP metanephric tubule formation
GO:0072210 IMP metanephric nephron development
GO:0072273 IMP metanephric nephron morphogenesis
GO:0090002 ISS establishment of protein localization to plasma membrane
GO:0090090 ISS negative regulation of canonical Wnt signaling pathway
GO:0090263 ISS positive regulation of canonical Wnt signaling pathway
GO:2000019 ISS negative regulation of male gonad development
GO:2000066 ISS positive regulation of cortisol biosynthetic process
GO:2000225 IMP negative regulation of testosterone biosynthetic process
GO:2001234 IGI negative regulation of apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000071208 wnt4a wingless-type MMTV integration site family, member 4a protein_coding Danio_rerio
ENSG00000162552 WNT4 wingless-type MMTV integration site family, member 4 protein_coding Homo_sapiens

Loading