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I18n::translate() - CORE/Cake/I18n/I18n.php, line 237
__d - CORE/Cake/basics.php, line 617
Cache::write() - CORE/Cake/Cache/Cache.php, line 321
DataSource::listSources() - CORE/Cake/Model/Datasource/DataSource.php, line 110
Mysql::listSources() - CORE/Cake/Model/Datasource/Database/Mysql.php, line 219
Model::setSource() - CORE/Cake/Model/Model.php, line 1142
Model::getDataSource() - CORE/Cake/Model/Model.php, line 3551
Model::__call() - CORE/Cake/Model/Model.php, line 808
Gene::findByid() - APP/Controller/GeneController.php, line 302
GeneController::show() - APP/Controller/GeneController.php, line 302
ReflectionMethod::invokeArgs() - [internal], line ??
Controller::invokeAction() - CORE/Cake/Controller/Controller.php, line 490
Dispatcher::_invoke() - CORE/Cake/Routing/Dispatcher.php, line 191
Dispatcher::dispatch() - CORE/Cake/Routing/Dispatcher.php, line 165
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DataSource::listSources() - CORE/Cake/Model/Datasource/DataSource.php, line 110
Mysql::listSources() - CORE/Cake/Model/Datasource/Database/Mysql.php, line 219
Model::setSource() - CORE/Cake/Model/Model.php, line 1142
Model::getDataSource() - CORE/Cake/Model/Model.php, line 3551
Model::__call() - CORE/Cake/Model/Model.php, line 808
Gene::findByid() - APP/Controller/GeneController.php, line 302
GeneController::show() - APP/Controller/GeneController.php, line 302
ReflectionMethod::invokeArgs() - [internal], line ??
Controller::invokeAction() - CORE/Cake/Controller/Controller.php, line 490
Dispatcher::_invoke() - CORE/Cake/Routing/Dispatcher.php, line 191
Dispatcher::dispatch() - CORE/Cake/Routing/Dispatcher.php, line 165
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DataSource::listSources() - CORE/Cake/Model/Datasource/DataSource.php, line 110
Mysql::listSources() - CORE/Cake/Model/Datasource/Database/Mysql.php, line 236
Model::setSource() - CORE/Cake/Model/Model.php, line 1142
Model::getDataSource() - CORE/Cake/Model/Model.php, line 3551
Model::__call() - CORE/Cake/Model/Model.php, line 808
Gene::findByid() - APP/Controller/GeneController.php, line 302
GeneController::show() - APP/Controller/GeneController.php, line 302
ReflectionMethod::invokeArgs() - [internal], line ??
Controller::invokeAction() - CORE/Cake/Controller/Controller.php, line 490
Dispatcher::_invoke() - CORE/Cake/Routing/Dispatcher.php, line 191
Dispatcher::dispatch() - CORE/Cake/Routing/Dispatcher.php, line 165
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DataSource::_cacheDescription() - CORE/Cake/Model/Datasource/DataSource.php, line 310
DataSource::describe() - CORE/Cake/Model/Datasource/DataSource.php, line 135
Mysql::describe() - CORE/Cake/Model/Datasource/Database/Mysql.php, line 332
Model::schema() - CORE/Cake/Model/Model.php, line 1372
DboSource::fields() - CORE/Cake/Model/Datasource/DboSource.php, line 2491
DboSource::read() - CORE/Cake/Model/Datasource/DboSource.php, line 1054
Model::_readDataSource() - CORE/Cake/Model/Model.php, line 2947
Model::find() - CORE/Cake/Model/Model.php, line 2919
DboSource::query() - CORE/Cake/Model/Datasource/DboSource.php, line 597
Model::__call() - CORE/Cake/Model/Model.php, line 808
Gene::findByid() - APP/Controller/GeneController.php, line 302
GeneController::show() - APP/Controller/GeneController.php, line 302
ReflectionMethod::invokeArgs() - [internal], line ??
Controller::invokeAction() - CORE/Cake/Controller/Controller.php, line 490
Dispatcher::_invoke() - CORE/Cake/Routing/Dispatcher.php, line 191
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Model::find() - CORE/Cake/Model/Model.php, line 2919
DboSource::query() - CORE/Cake/Model/Datasource/DboSource.php, line 597
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GeneController::show() - APP/Controller/GeneController.php, line 302
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Controller::invokeAction() - CORE/Cake/Controller/Controller.php, line 490
Dispatcher::_invoke() - CORE/Cake/Routing/Dispatcher.php, line 191
Dispatcher::dispatch() - CORE/Cake/Routing/Dispatcher.php, line 165
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Institute of Cardiovascular Regeneration Webtool Repository
C-It-Loci: A knowledge database for tissue-enriched loci.
Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main
Expression Patterns
Heat Map
Numeric Values
Transcript ';
Adipose Adrenal Bladder Brain Breast Colon Liver Lung Ovary Placenta ENSMUST00000117872 ENSMUST00000119260 ENSMUST00000120141 ENSMUST00000120187 ENSMUST00000122054 ENSMUST00000124096 ENSMUST00000130557 ENSMUST00000153166
Transcript ID
Adipose
Adrenal
Bladder
Brain
Breast
Colon
Liver
Lung
Ovary
Placenta
ENSMUST00000117872
8.585±4.61
11.104±1.60
9.549±0.78
4.891±1.79
5.089±0.00
5.710±0.86
2.500±1.17
7.626±0.36
10.750±3.29
3.250±0.09
ENSMUST00000119260
N/A
N/A
N/A
4.437±0.00
N/A
N/A
N/A
N/A
N/A
N/A
ENSMUST00000120141
N/A
N/A
N/A
N/A
N/A
N/A
N/A
N/A
11.500±0.00
14.851±2.67
ENSMUST00000120187
N/A
11.047±1.94
N/A
N/A
8.863±1.95
7.950±1.55
1.892±0.21
16.072±3.16
8.250±0.93
9.192±0.00
ENSMUST00000122054
N/A
N/A
N/A
3.314±0.00
N/A
N/A
N/A
N/A
8.791±0.00
8.264±1.46
ENSMUST00000124096
N/A
N/A
11.848±2.11
N/A
12.555±2.69
N/A
3.400±0.80
19.462±2.24
15.958±3.49
6.018±0.00
ENSMUST00000130557
N/A
N/A
N/A
N/A
18.360±0.00
N/A
N/A
N/A
N/A
N/A
ENSMUST00000153166
N/A
8.777±0.25
5.327±0.00
N/A
4.171±0.00
5.548±0.58
1.918±0.64
13.417±2.71
8.478±0.71
N/A
Conserved Regions
Region ID Sub-Region Region Type Position
CIL_0002WI
CIL_0002WI_0002
CGP
7:129591863-133123350
CIL_0007TN
CIL_0007TN_0002
VISTA
7:129759548-130361335
CIL_00095T
CIL_00095T_0002
VISTA
7:130125765-130727321
CIL_0001BE
CIL_0001BE_0002
CGP
7:130162451-133123350
Gene Ontology
GO ID Evidence Type GO Description
GO:0000122
IMP
negative regulation of transcription from RNA polymerase II promoter
GO:0001525
IGI
angiogenesis
GO:0001657
IGI
ureteric bud development
GO:0001701
IGI
in utero embryonic development
GO:0001837
IEA
epithelial to mesenchymal transition
GO:0002053
IGI
positive regulation of mesenchymal cell proliferation
GO:0003148
IMP
outflow tract septum morphogenesis
GO:0003149
IMP
membranous septum morphogenesis
GO:0005007
IEA
fibroblast growth factor-activated receptor activity
GO:0005515
IPI
protein binding
GO:0005524
IEA
ATP binding
GO:0005576
TAS
extracellular region
GO:0005634
IDA
nucleus
GO:0005737
IEA
cytoplasm
GO:0005887
IEA
integral component of plasma membrane
GO:0005938
IEA
cell cortex
GO:0007267
IMP
cell-cell signaling
GO:0007409
IMP
axonogenesis
GO:0007528
IMP
neuromuscular junction development
GO:0008284
IMP
positive regulation of cell proliferation
GO:0008285
IGI
negative regulation of cell proliferation
GO:0008543
IGI
fibroblast growth factor receptor signaling pathway
GO:0008589
IMP
regulation of smoothened signaling pathway
GO:0009791
IMP
post-embryonic development
GO:0009880
IMP
embryonic pattern specification
GO:0009887
IMP
organ morphogenesis
GO:0009986
IEA
cell surface
GO:0010453
IMP
regulation of cell fate commitment
GO:0010518
IEA
positive regulation of phospholipase activity
GO:0016021
IEA
integral component of membrane
GO:0016331
IMP
morphogenesis of embryonic epithelium
GO:0017134
IDA
fibroblast growth factor binding
GO:0018108
IEA
peptidyl-tyrosine phosphorylation
GO:0022612
IMP
gland morphogenesis
GO:0030177
IMP
positive regulation of Wnt signaling pathway
GO:0030282
IMP
bone mineralization
GO:0030324
IMP
lung development
GO:0030855
IMP
epithelial cell differentiation
GO:0030901
IGI
midbrain development
GO:0030916
IMP
otic vesicle formation
GO:0031012
IEA
extracellular matrix
GO:0031069
IMP
hair follicle morphogenesis
GO:0032808
IMP
lacrimal gland development
GO:0035264
IMP
multicellular organism growth
GO:0035265
IMP
organ growth
GO:0040014
IMP
regulation of multicellular organism growth
GO:0040036
IMP
regulation of fibroblast growth factor receptor signaling pathway
GO:0042127
IMP
regulation of cell proliferation
GO:0042472
IMP
inner ear morphogenesis
GO:0042476
IMP
odontogenesis
GO:0042803
IEA
protein homodimerization activity
GO:0043231
IEA
intracellular membrane-bounded organelle
GO:0043410
IEA
positive regulation of MAPK cascade
GO:0045165
IDA
cell fate commitment
GO:0045839
IGI
negative regulation of mitosis
GO:0045944
IMP
positive regulation of transcription from RNA polymerase II promoter
GO:0046777
IEA
protein autophosphorylation
GO:0048286
IGI
lung alveolus development
GO:0048333
IEA
mesodermal cell differentiation
GO:0048489
IMP
synaptic vesicle transport
GO:0048557
IMP
embryonic digestive tract morphogenesis
GO:0048562
IMP
embryonic organ morphogenesis
GO:0048565
IMP
digestive tract development
GO:0048568
IMP
embryonic organ development
GO:0048608
IMP
reproductive structure development
GO:0048661
IEA
positive regulation of smooth muscle cell proliferation
GO:0048701
IEA
embryonic cranial skeleton morphogenesis
GO:0048730
IMP
epidermis morphogenesis
GO:0048755
IMP
branching morphogenesis of a nerve
GO:0048762
IGI
mesenchymal cell differentiation
GO:0050673
IMP
epithelial cell proliferation
GO:0050678
IMP
regulation of epithelial cell proliferation
GO:0050679
IGI
positive regulation of epithelial cell proliferation
GO:0050680
IEA
negative regulation of epithelial cell proliferation
GO:0051150
IMP
regulation of smooth muscle cell differentiation
GO:0051781
IMP
positive regulation of cell division
GO:0055010
IMP
ventricular cardiac muscle tissue morphogenesis
GO:0060045
IGI
positive regulation of cardiac muscle cell proliferation
GO:0060174
IMP
limb bud formation
GO:0060348
IMP
bone development
GO:0060349
IMP
bone morphogenesis
GO:0060365
IMP
coronal suture morphogenesis
GO:0060441
IMP
epithelial tube branching involved in lung morphogenesis
GO:0060442
IMP
branching involved in prostate gland morphogenesis
GO:0060445
IMP
branching involved in salivary gland morphogenesis
GO:0060449
IMP
bud elongation involved in lung branching
GO:0060463
IMP
lung lobe morphogenesis
GO:0060484
IMP
lung-associated mesenchyme development
GO:0060501
IMP
positive regulation of epithelial cell proliferation involved in lung morphogenesis
GO:0060512
IMP
prostate gland morphogenesis
GO:0060523
IMP
prostate epithelial cord elongation
GO:0060527
IMP
prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis
GO:0060529
IMP
squamous basal epithelial stem cell differentiation involved in prostate gland acinus development
GO:0060595
IMP
fibroblast growth factor receptor signaling pathway involved in mammary gland specification
GO:0060601
IMP
lateral sprouting from an epithelium
GO:0060615
IMP
mammary gland bud formation
GO:0060664
IGI
epithelial cell proliferation involved in salivary gland morphogenesis
GO:0060667
IGI
branch elongation involved in salivary gland morphogenesis
GO:0060670
IMP
branching involved in labyrinthine layer morphogenesis
GO:0060687
IMP
regulation of branching involved in prostate gland morphogenesis
GO:0060688
IMP
regulation of morphogenesis of a branching structure
GO:0060915
IGI
mesenchymal cell differentiation involved in lung development
GO:0060916
IMP
mesenchymal cell proliferation involved in lung development
GO:0061031
IMP
endodermal digestive tract morphogenesis
GO:0070307
IGI
lens fiber cell development
GO:0070372
IMP
regulation of ERK1 and ERK2 cascade
GO:0070374
IGI
positive regulation of ERK1 and ERK2 cascade
GO:0090263
IMP
positive regulation of canonical Wnt signaling pathway
Homologs
ENSEMBL Accession
Gene Name
Description
Biotype
Species
ENSDARG00000058115
fgfr2
fibroblast growth factor receptor 2
protein_coding
Danio_rerio
ENSG00000066468
FGFR2
fibroblast growth factor receptor 2
protein_coding
Homo_sapiens
Loading
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'Component' => '/var/www/c-it-loci/lib/Cake/Controller/Component.php',
'RequestHandlerComponent' => '/var/www/c-it-loci/lib/Cake/Controller/Component/RequestHandlerComponent.php',
'ClassRegistry' => '/var/www/c-it-loci/lib/Cake/Utility/ClassRegistry.php',
'Gene' => '/var/www/c-it-loci/app/Model/Gene.php',
'AppModel' => '/var/www/c-it-loci/app/Model/AppModel.php',
'Model' => '/var/www/c-it-loci/lib/Cake/Model/Model.php',
'BehaviorCollection' => '/var/www/c-it-loci/lib/Cake/Model/BehaviorCollection.php',
'ConnectionManager' => '/var/www/c-it-loci/lib/Cake/Model/ConnectionManager.php',
'Mysql' => '/var/www/c-it-loci/lib/Cake/Model/Datasource/Database/Mysql.php',
'DboSource' => '/var/www/c-it-loci/lib/Cake/Model/Datasource/DboSource.php',
'DataSource' => '/var/www/c-it-loci/lib/Cake/Model/Datasource/DataSource.php',
'I18n' => '/var/www/c-it-loci/lib/Cake/I18n/I18n.php',
'L10n' => '/var/www/c-it-loci/lib/Cake/I18n/L10n.php',
'CakeSession' => '/var/www/c-it-loci/lib/Cake/Model/Datasource/CakeSession.php',
'View' => '/var/www/c-it-loci/lib/Cake/View/View.php',
'HelperCollection' => '/var/www/c-it-loci/lib/Cake/View/HelperCollection.php',
'ViewBlock' => '/var/www/c-it-loci/lib/Cake/View/ViewBlock.php',
'HtmlHelper' => '/var/www/c-it-loci/lib/Cake/View/Helper/HtmlHelper.php',
'AppHelper' => '/var/www/c-it-loci/app/View/Helper/AppHelper.php',
'Helper' => '/var/www/c-it-loci/lib/Cake/View/Helper.php',
'FormHelper' => '/var/www/c-it-loci/lib/Cake/View/Helper/FormHelper.php',
'SessionHelper' => '/var/www/c-it-loci/lib/Cake/View/Helper/SessionHelper.php'
)
$config = '_cake_core_'
$settings = array(
'prefix' => '*****',
'engine' => 'File',
'path' => '/var/www/c-it-loci/app/tmp/cache/persistent/',
'serialize' => true,
'duration' => (int) 10,
'lock' => true,
'isWindows' => false,
'mask' => (int) 436,
'probability' => (int) 100,
'groups' => array()
)
$success = false Cache::write() - CORE/Cake/Cache/Cache.php, line 323
App::shutdown() - CORE/Cake/Core/App.php, line 899
[main] - [internal], line ?? Warning (512) : _cake_core_ cache was unable to write 'method_cache' to File cache [CORE/Cake/Cache/Cache.php , line 323 ]Code Context ),
E_USER_WARNING
); $key = 'method_cache'
$value = array(
(int) 0 => false,
'name' => array(
'45b989c52610ac6d773f6b83d6108190' => '`citloci`',
'4d0d73f550e4b0573d9cf666d63a0244' => '`genes`',
'003d5968b53baeeb0cb27d56c4d447af' => '`Gene`.`id`',
'f32f1dc049466870a2299961f0604112' => '`Gene`.`gene_version`',
'433a39b330b04a021541e6fa89d80ffd' => '`Gene`.`tax_id`',
'56705ff3488da428f13156180dbc9fbc' => '`Gene`.`assembly`',
'b7d572bb36c8f0f2ecfe36921c14fbf3' => '`Gene`.`chromosome`',
'edf6b12f8a40424f91fa0a40f0eab275' => '`Gene`.`strand`',
'71d92ec0ad29837870abd0de3ae8addc' => '`Gene`.`start`',
'62e43d606bf4cdae2d6694c62e19e7fa' => '`Gene`.`end`',
'7043386674301bd31c5e629dfdadabd4' => '`Gene`.`gene_name`',
'f1454297621ddcf07c418e47f67d3857' => '`Gene`.`gene_source`',
'27d53785bfcd771f1901030b4bb87d02' => '`Gene`.`gene_biotype`',
'b93574bf8a03f2d6f6486e920115e0d1' => '`Gene`.`annotation_version`',
'1c4a3f5d90070e8ea1c62ca077df603e' => '`Gene`.`gene_description`',
'8ca7a0c53312b8ae3cfa40a9d814adac' => '`Gene`'
),
'fields' => array(
'0ea8c82680a14e2566476c4ab527af47' => array(
(int) 0 => '`Gene`.`id`',
(int) 1 => '`Gene`.`gene_version`',
(int) 2 => '`Gene`.`tax_id`',
(int) 3 => '`Gene`.`assembly`',
(int) 4 => '`Gene`.`chromosome`',
(int) 5 => '`Gene`.`strand`',
(int) 6 => '`Gene`.`start`',
(int) 7 => '`Gene`.`end`',
(int) 8 => '`Gene`.`gene_name`',
(int) 9 => '`Gene`.`gene_source`',
(int) 10 => '`Gene`.`gene_biotype`',
(int) 11 => '`Gene`.`annotation_version`',
(int) 12 => '`Gene`.`gene_description`'
)
)
)
$config = '_cake_core_'
$settings = array(
'prefix' => '*****',
'engine' => 'File',
'path' => '/var/www/c-it-loci/app/tmp/cache/persistent/',
'serialize' => true,
'duration' => (int) 10,
'lock' => true,
'isWindows' => false,
'mask' => (int) 436,
'probability' => (int) 100,
'groups' => array()
)
$success = false Cache::write() - CORE/Cake/Cache/Cache.php, line 323
DboSource::__destruct() - CORE/Cake/Model/Datasource/DboSource.php, line 3539
[main] - [internal], line ??