C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: interleukin 21
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000027718 Il21 10090 - 3:37222759-37232618 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000029273 Il21-001 37222759-37232618 protein_coding
  ENSMUST00000161015 Il21-002 37225337-37232565 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBrainMuscleOvaryPlacentaTestisENSMUST00000029273
Transcript ID Bladder Brain Muscle Ovary Placenta Testis
ENSMUST00000029273 0.005±0.00 0.017±0.01 0.018±0.00 0.005±0.00 0.004±0.00 0.074±0.03

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007AF CIL_0007AF_0002 CGP 3:37120523-37232618

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001783 NAS B cell apoptotic process
GO:0002729 IDA positive regulation of natural killer cell cytokine production
GO:0005125 IEA cytokine activity
GO:0005126 IDA cytokine receptor binding
GO:0005134 IEA interleukin-2 receptor binding
GO:0005615 IEA extracellular space
GO:0006955 IEA immune response
GO:0008284 IEA positive regulation of cell proliferation
GO:0030890 IEA positive regulation of B cell proliferation
GO:0032733 IDA positive regulation of interleukin-10 production
GO:0032740 IEA positive regulation of interleukin-17 production
GO:0032825 IDA positive regulation of natural killer cell differentiation
GO:0042102 IEA positive regulation of T cell proliferation
GO:0042511 IEA positive regulation of tyrosine phosphorylation of Stat1 protein
GO:0042517 IEA positive regulation of tyrosine phosphorylation of Stat3 protein
GO:0045078 IDA positive regulation of interferon-gamma biosynthetic process
GO:0045579 NAS positive regulation of B cell differentiation
GO:0045954 IDA positive regulation of natural killer cell mediated cytotoxicity
GO:0048469 IEA cell maturation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000138684 IL21 interleukin 21 protein_coding Homo_sapiens

Loading