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Institute of Cardiovascular Regeneration Webtool Repository

C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: poly (ADP-ribose) polymerase 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000129484 PARP2 9606 + 14:20343582-20357905 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000250416 PARP2-002 20343615-20357904 protein_coding
  ENST00000429687 PARP2-001 20343582-20357905 protein_coding
  ENST00000527384 PARP2-009 20354642-20355955 retained_intron
  ENST00000527915 PARP2-003 20343637-20357903 protein_coding
  ENST00000528465 PARP2-006 20350699-20354108 retained_intron
  ENST00000529465 PARP2-012 20343628-20354947 nonsense_mediated_decay
  ENST00000530598 PARP2-010 20355796-20357509 retained_intron
  ENST00000532299 PARP2-007 20355161-20356392 retained_intron
  ENST00000534664 PARP2-008 20355910-20356750 retained_intron
  ENST00000539930 PARP2-013 20355782-20357776 protein_coding
  ENST00000555140 PARP2-014 20352513-20354123 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000250416ENST00000429687ENST00000527915ENST00000539930
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000250416 1.597±0.00 N/A 4.404±0.00 5.792±0.00 N/A 3.070±0.00 N/A 1.128±0.00 N/A N/A N/A 2.508±0.16 N/A
ENST00000429687 N/A N/A N/A N/A 3.492±0.00 2.116±0.00 5.685±0.00 0.606±0.00 2.451±0.00 5.974±0.00 5.204±3.02 4.070±1.10 9.141±4.08
ENST00000527915 N/A 4.635±0.00 4.095±0.00 N/A N/A N/A N/A N/A 1.801±0.00 N/A 3.581±0.60 N/A 6.871±0.00
ENST00000539930 N/A N/A N/A N/A N/A N/A N/A 2.385±0.00 N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001OD CIL_0001OD_0001 CGP 14:20311368-20357905
CIL_0001OA CIL_0001OA_0001 CGP 14:20343582-20413429

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003677 IEA DNA binding
GO:0003950 IEA NAD+ ADP-ribosyltransferase activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 IDA nucleoplasm
GO:0005730 IDA nucleolus
GO:0006281 TAS DNA repair
GO:0006284 IEA base-excision repair
GO:0006471 IEA protein ADP-ribosylation
GO:0097191 IEA extrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000079202 parp2 poly (ADP-ribose) polymerase family, member 2 protein_coding Danio_rerio
ENSMUSG00000036023 Parp2 poly (ADP-ribose) polymerase family, member 2 protein_coding Mus_musculus

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