C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: histidine-rich glycoprotein
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000113905 HRG 9606 + 3:186660216-186678240 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000232003 HRG-001 186665952-186678240 protein_coding
  ENST00000468154 HRG-003 186660216-186666181 processed_transcript
  ENST00000495413 HRG-002 186668978-186678231 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000232003ENST00000468154ENST00000495413
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000232003 N/A N/A 3.293±0.00 0.132±0.00 1.226±0.00 N/A N/A 204.761±201.94 140.646±140.58 N/A 0.086±0.00 0.035±0.01 0.046±0.00 N/A
ENST00000468154 0.306±0.00 1.696±0.00 N/A 0.238±0.00 0.357±0.00 0.368±0.11 0.038±0.00 N/A N/A 0.539±0.00 0.105±0.00 0.122±0.01 0.124±0.00 0.513±0.00
ENST00000495413 0.026±0.00 N/A N/A 0.079±0.00 0.063±0.00 0.040±0.00 0.016±0.00 N/A N/A 0.025±0.00 0.003±0.00 0.008±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008PR CIL_0008PR_0001 VISTA 3:186106052-186707543
CIL_000044 CIL_000044_0001 CGP 3:186635969-186678240
CIL_0008LA CIL_0008LA_0001 VISTA 3:186647123-187250687
CIL_000043 CIL_000043_0001 CGP 3:186660216-186743954

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001525 IEA angiogenesis
GO:0002576 TAS platelet degranulation
GO:0002839 IDA positive regulation of immune response to tumor cell
GO:0004867 IEA serine-type endopeptidase inhibitor activity
GO:0004869 IEA cysteine-type endopeptidase inhibitor activity
GO:0005102 IDA receptor binding
GO:0005515 IPI protein binding
GO:0005576 NAS extracellular region
GO:0005886 TAS plasma membrane
GO:0006935 IEA chemotaxis
GO:0007162 IDA negative regulation of cell adhesion
GO:0007596 TAS blood coagulation
GO:0008201 IDA heparin binding
GO:0008270 IDA zinc ion binding
GO:0008285 IDA negative regulation of cell proliferation
GO:0010468 IDA regulation of gene expression
GO:0010543 ISS regulation of platelet activation
GO:0010593 IDA negative regulation of lamellipodium assembly
GO:0010951 IEA negative regulation of endopeptidase activity
GO:0014070 IEA response to organic cyclic compound
GO:0015886 IEA heme transport
GO:0016525 IDA negative regulation of angiogenesis
GO:0019865 IDA immunoglobulin binding
GO:0020037 IDA heme binding
GO:0030168 IDA platelet activation
GO:0030193 IDA regulation of blood coagulation
GO:0030308 IDA negative regulation of cell growth
GO:0031093 TAS platelet alpha granule lumen
GO:0031982 IEA vesicle
GO:0032956 IDA regulation of actin cytoskeleton organization
GO:0033629 IDA negative regulation of cell adhesion mediated by integrin
GO:0034395 IEA regulation of transcription from RNA polymerase II promoter in response to iron
GO:0036019 IEA endolysosome
GO:0042730 TAS fibrinolysis
GO:0043065 IDA positive regulation of apoptotic process
GO:0043254 IDA regulation of protein complex assembly
GO:0043395 IDA heparan sulfate proteoglycan binding
GO:0043537 ISS negative regulation of blood vessel endothelial cell migration
GO:0046872 IDA metal ion binding
GO:0050730 IDA regulation of peptidyl-tyrosine phosphorylation
GO:0050832 IDA defense response to fungus
GO:0051894 IDA positive regulation of focal adhesion assembly
GO:0051918 IEA negative regulation of fibrinolysis
GO:0061474 IEA phagolysosome membrane
GO:0070062 IDA extracellular vesicular exosome
GO:0072562 IDA blood microparticle
GO:0097037 IEA heme export
GO:1900747 IDA negative regulation of vascular endothelial growth factor signaling pathway
GO:2000504 IDA positive regulation of blood vessel remodeling
GO:2001027 IDA negative regulation of endothelial cell chemotaxis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000022877 Hrg histidine-rich glycoprotein protein_coding Mus_musculus

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