C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: fibroblast growth factor receptor 1a
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000011027 fgfr1a 7955 - 8:53708709-53802565 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000024882 fgfr1a-003 53712672-53785256 protein_coding
  ENSDART00000074774 fgfr1a-201 53712608-53785291 protein_coding
  ENSDART00000127119 fgfr1a-004 53712608-53785291 nonsense_mediated_decay
  ENSDART00000135166 fgfr1a-002 53712608-53785291 protein_coding
  ENSDART00000147742 fgfr1a-001 53708709-53802565 protein_coding
  ENSDART00000149261 fgfr1a-006 53750014-53785189 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartLiverENSDART00000074774ENSDART00000147742
Transcript ID Brain Heart Liver
ENSDART00000074774 N/A N/A 0.066±0.00
ENSDART00000147742 0.376±0.00 1.384±0.00 0.028±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000166 IEA nucleotide binding
GO:0001889 IMP liver development
GO:0004672 IEA protein kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0004714 IEA transmembrane receptor protein tyrosine kinase activity
GO:0005007 IEA fibroblast growth factor-activated receptor activity
GO:0005515 IEA protein binding
GO:0005524 IEA ATP binding
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0005829 IEA cytosol
GO:0005886 ISS plasma membrane
GO:0005887 ISS integral to plasma membrane
GO:0006468 IEA protein phosphorylation
GO:0008201 ISS heparin binding
GO:0008284 IEA positive regulation of cell proliferation
GO:0008543 IEA fibroblast growth factor receptor signaling pathway
GO:0009953 IMP dorsal/ventral pattern formation
GO:0010863 ISS positive regulation of phospholipase C activity
GO:0016020 IEA membrane
GO:0016021 IEA integral to membrane
GO:0016023 IEA cytoplasmic membrane-bounded vesicle
GO:0016301 IEA kinase activity
GO:0016310 IEA phosphorylation
GO:0016740 IEA transferase activity
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0017134 ISS fibroblast growth factor binding
GO:0018108 IDA peptidyl-tyrosine phosphorylation
GO:0031101 IMP fin regeneration
GO:0031410 IEA cytoplasmic vesicle
GO:0036342 IGI post-anal tail morphogenesis
GO:0042664 IGI negative regulation of endodermal cell fate specification
GO:0043406 ISS positive regulation of MAP kinase activity
GO:0043589 IMP skin morphogenesis
GO:0048738 IMP cardiac muscle tissue development
GO:0048916 IMP posterior lateral line development
GO:0060173 IEA limb development
GO:0060249 IMP anatomical structure homeostasis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000077782 FGFR1 fibroblast growth factor receptor 1 protein_coding Homo_sapiens
ENSMUSG00000031565 Fgfr1 fibroblast growth factor receptor 1 protein_coding Mus_musculus

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