C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: intersectin 1 (SH3 domain protein)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000000086 itsn1 7955 - 1:47492921-47586925 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000000087 itsn1-201 47492921-47569055 protein_coding
  ENSDART00000132378 itsn1-001 47496548-47586925 protein_coding
  ENSDART00000139573 itsn1-002 47516118-47569055 processed_transcript
  ENSDART00000150545 itsn1-003 47563600-47586925 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000000087ENSDART00000139573
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000000087 4.018±2.52 2.873±0.84 1.025±0.05 0.145±0.00 0.607±0.00
ENSDART00000139573 N/A 1.913±0.00 1.603±0.00 N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005085 IEA guanyl-nucleotide exchange factor activity
GO:0005089 IEA Rho guanyl-nucleotide exchange factor activity
GO:0005509 IEA calcium ion binding
GO:0005515 IEA protein binding
GO:0006897 IEA endocytosis
GO:0035023 IEA regulation of Rho protein signal transduction
GO:0035556 IEA intracellular signal transduction

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000205726 ITSN1 intersectin 1 (SH3 domain protein) protein_coding Homo_sapiens
ENSMUSG00000022957 Itsn1 intersectin 1 (SH3 domain protein 1A) protein_coding Mus_musculus

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